Dipyridamole is contraindicated as a sole treatment in elderly patients primarily due to:

Dipyridamole is contraindicated as a sole treatment in elderly patients primarily due to concerns about gastrointestinal effects and orthostasis. In elderly individuals, there is a heightened sensitivity to medications, which can lead to increased side effects and adverse reactions.

Gastrointestinal issues, such as dyspepsia and diarrhea, can significantly impact the quality of life for elderly patients, who may already be managing multiple health issues. Additionally, the risk of orthostatic hypotension—where a sudden change in position can lead to drops in blood pressure and resultant dizziness or fainting—is particularly relevant in this population. The elderly often have compromised cardiovascular systems, making them more vulnerable to these risks, especially when medications like dipyridamole are used without additional protective treatments.

While other options may highlight potential risks associated with dipyridamole, none articulate the direct and immediate implications of GI issues and the propensity for orthostatic hypotension, which are critical in managing the health of elderly patients.