Thrombin receptor is also known as?

Study for the Antiplatelet Agents Test. Use flashcards and multiple choice questions with hints and explanations. Get ready for your exam!

The thrombin receptor is indeed known as PAR-1, which stands for Protease-Activated Receptor 1. This receptor is a part of the family of G protein-coupled receptors and is activated by thrombin, a key enzyme in the coagulation cascade. Upon activation, PAR-1 plays a significant role in platelet activation and aggregation, as well as in various cellular responses to injury, inflammation, and vascular repair.

The alternative choices are associated with different receptors or proteins involved in platelet function and hemostasis. GP IIb/IIIa is a receptor complex that plays a crucial role in platelet aggregation by binding fibrinogen. PDE3 refers to phosphodiesterase type 3, an enzyme that degrades cAMP and cGMP, thereby influencing platelet function. The ADP receptor, specifically the P2Y12 receptor, is crucial for mediating the effects of ADP in platelet activation. However, none of these options directly refer to thrombin receptors, reinforcing that PAR-1 is the correct identification for the thrombin receptor.

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