Urokinase is isolated from cultures of which type of cells?

Urokinase is an enzyme that plays a crucial role in the process of fibrinolysis, which is the breakdown of fibrin in blood clots. It is particularly important in medical applications such as thrombolytic therapy for treating clots. Urokinase is derived from human fetal kidney cells, making this choice correct.

The isolation of urokinase from these kidney cells is significant because it reflects the biological functions of the kidneys, which produce various enzymes and proteins vital for hemostasis and immune responses. The fetal aspect emphasizes that certain enzymes have developmental origins, with urokinase being originally discovered in such cells.

Understanding the source of urokinase is essential for those studying its therapeutic applications, as the isolation technique influences availability, production methods, and potential uses in clinical settings. Knowing that it originates from human fetal kidney cells can also help elucidate its mechanism of action and efficacy in dissolving clots in patients.