What are two adverse effects of urokinase?

Urokinase, a thrombolytic agent used to dissolve blood clots, is associated with specific adverse effects that are important to recognize. Among these, bleeding is a primary concern due to the mechanism of action of thrombolytics, which can inadvertently cause both minor and major hemorrhages. This risk is heightened in patients with predisposing factors such as active bleeding, recent surgery, or certain coagulopathies.

Furthermore, rare allergic reactions can occur. These reactions may include symptoms such as rash or anaphylaxis in very sensitive individuals. While allergic reactions are not as common as bleeding, their potential occurrence emphasizes the need for careful monitoring after administration of urokinase.

The other options provided involve symptoms that may be seen in various clinical scenarios but are not typically recognized as direct adverse effects of urokinase specifically. Thus, acknowledging bleeding and rare allergic reactions as adverse effects encapsulates the critical safety considerations when using this medication in clinical practice.