What is the generic name for Tissue Plasminogen Activator?

The generic name for Tissue Plasminogen Activator is Alteplase. This medication is a thrombolytic agent used to dissolve blood clots that can cause serious conditions such as myocardial infarction (heart attack) or ischemic stroke.

Alteplase works by promoting the conversion of plasminogen to plasmin, which is an enzyme that breaks down fibrin in blood clots. This action helps restore blood flow to the affected tissues and can significantly reduce the risk of permanent damage when administered promptly.

While other listed agents, such as Streptokinase, Tenecteplase, and Reteplase, are also thrombolytics used for similar purposes, they are different compounds with distinct properties and mechanisms of action. For instance, Streptokinase is derived from streptococci bacteria, whereas Tenecteplase and Reteplase are engineered derivatives of alteplase with enhancements for faster thrombolytic activity. However, only Alteplase is directly identified as the generic name for Tissue Plasminogen Activator.