What is the typical dose of aspirin recommended to be used with Ticagrelor?

The typical dose of aspirin recommended to be used with Ticagrelor is 100 mg. This combination is important in the management of patients with acute coronary syndromes and those who have undergone percutaneous coronary intervention. Aspirin works as an antiplatelet agent by inhibiting cyclooxygenase and subsequently the formation of thromboxane A2, which is a potent promoter of platelet aggregation.

Using 100 mg of aspirin alongside Ticagrelor is beneficial because it enhances the antiplatelet effect without significantly increasing the risk of major bleeding compared to higher doses. Higher doses of aspirin, like 150 mg or 200 mg, are generally not recommended as they do not provide additional benefit in terms of preventing thrombotic events but may increase the risk of bleeding complications. A lower dose, such as 50 mg, is below the standard recommendation and may not provide optimal protection against thrombotic events in the patient population for whom Ticagrelor is typically prescribed.