What is Tirofiban's half-life?

Tirofiban is an antiplatelet agent that works by inhibiting the glycoprotein IIb/IIIa receptor on platelets, which is critical for platelet aggregation. Understanding its pharmacokinetics is essential for effective clinical use, particularly in urgent settings such as acute coronary syndromes and percutaneous coronary interventions.

The half-life of Tirofiban is approximately 2 hours. This duration is significant as it allows for relatively quick recovery of platelet function once the drug is discontinued, which is advantageous in situations where patients may require surgical interventions soon after the infusion is stopped.

In clinical practice, knowing Tirofiban's half-life aids healthcare professionals in making informed decisions regarding the timing of surgical procedures and the management of potential bleeding risks associated with antiplatelet therapy. The 2-hour half-life also means that the drug can be effectively used in a continuous intravenous infusion for appropriate time intervals, ensuring optimal antiplatelet effects.